Author: Johnson, Bryan A.; Graham, Rachel L.; Menachery, Vineet D.
Title: Viral metagenomics, protein structure, and reverse genetics: key strategies for investigating coronaviruses Cord-id: 6vja5e5o Document date: 2018_4_1
ID: 6vja5e5o
Snippet: Viral metagenomics, modeling of protein structure, and manipulation of viral genetics are key approaches that have laid the foundations of our understanding of coronavirus biology. In this review, we discuss the major advances each method has provided and discuss how future studies should leverage these strategies synergistically to answer novel questions.
Document: Viral metagenomics, modeling of protein structure, and manipulation of viral genetics are key approaches that have laid the foundations of our understanding of coronavirus biology. In this review, we discuss the major advances each method has provided and discuss how future studies should leverage these strategies synergistically to answer novel questions.
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