Author: Yueping Li; Zhiwei Xie; Weiyin Lin; Weiping Cai; Chunyan Wen; Yujuan Guan; Xiaoneng Mo; Jian Wang; Yaping Wang; Ping Peng; Xudan Chen; Wenxin Hong; Guangming Xiao; Jinxin Liu; Lieguang Zhang; Fengyu Hu; Feng Li; Feng Li; Fuchun Zhang; Xilong Deng; Linghua Li
Title: An exploratory randomized, controlled study on the efficacy and safety of lopinavir/ritonavir or arbidol treating adult patients hospitalized with mild/moderate COVID-19 (ELACOI) Document date: 2020_3_23
ID: 9hknw4ws_15
Snippet: All participants met the following inclusion criteria: 1) age between 18 and 80 years; 2) SARS-CoV-2 infection confirmed by real-time PCR (RT-PCR) from pharyngeal swab; 3) mild clinical status, defined as having mild clinical symptoms but no signs of pneumonia on imaging or moderate clinical status, defined as having fever, respiratory symptoms and pneumonia on imaging [5]; 4) the following lab findings: creatinine ≤ 110μmol/L, creatinine clea.....
Document: All participants met the following inclusion criteria: 1) age between 18 and 80 years; 2) SARS-CoV-2 infection confirmed by real-time PCR (RT-PCR) from pharyngeal swab; 3) mild clinical status, defined as having mild clinical symptoms but no signs of pneumonia on imaging or moderate clinical status, defined as having fever, respiratory symptoms and pneumonia on imaging [5]; 4) the following lab findings: creatinine ≤ 110μmol/L, creatinine clearance rate (eGFR) ≥ 60 ml/min/1.73m 2 , aspartate aminotransferase (AST) and alanine aminotransferase (ALT) ≤ 5 × ULN, and total bilirubin (TBIL) ≤ 2 × ULN; 5) willingness to participate in the study and provide informed consent. Patients All rights reserved. No reuse allowed without permission. author/funder, who has granted medRxiv a license to display the preprint in perpetuity.
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