Author: Ansori, A. N. M.
Title: In silico study of sars-cov-2 vaccine candidate: Spike glycoprotein Cord-id: bwteambr Document date: 2021_1_1
ID: bwteambr
Snippet: This study aimed to perform the analysis of toxicity prediction, allergenicity prediction, and in silico cloning of peptides originated from SARS-CoV-2 spike glycoprotein in the previous study. Allergenicity prediction employed AllerPred to predict the non-allergen peptides and toxicity prediction performed using ToxinPred. Then, this study designed the in silico cloning of SARS-CoV-2 spike glycoprotein with pET-28a(+) using SnapGene software. Therefore, this study successfully constructed the S
Document: This study aimed to perform the analysis of toxicity prediction, allergenicity prediction, and in silico cloning of peptides originated from SARS-CoV-2 spike glycoprotein in the previous study. Allergenicity prediction employed AllerPred to predict the non-allergen peptides and toxicity prediction performed using ToxinPred. Then, this study designed the in silico cloning of SARS-CoV-2 spike glycoprotein with pET-28a(+) using SnapGene software. Therefore, this study successfully constructed the SARS-CoV-2 vaccine candidate via in silico method. Therefore, these data could be used to design a peptide-based vaccine against SARS-CoV-2. However, the advanced study is recommended confirmation, such as in vitro and in vivo study.
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