Author: Nopp, Stephan; Janataâ€Schwatczek, Karin; Prosch, Helmut; Shulym, Ihor; Königsbrügge, Oliver; Pabinger, Ingrid; Ay, Cihan
Title: Pulmonary embolism during the COVIDâ€19 pandemic: decline in diagnostic procedures and incidence at a University Hospital Cord-id: 6xhyfgly Document date: 2020_5_20
ID: 6xhyfgly
Snippet: BACKGROUND: The COVIDâ€19 pandemic has focused medical attention on treating affected patients and protecting others from infection. However, concerns have been raised regarding the pandemic´s impact and associated containment measures (e.g. curfew, lockdown) on nonâ€COVIDâ€19â€related acute medical diseases. OBJECTIVES: To investigate changes in the incidence of pulmonary embolism (PE) during the COVIDâ€19 pandemic compared to the period prior to the pandemic and reference periods in prev
Document: BACKGROUND: The COVIDâ€19 pandemic has focused medical attention on treating affected patients and protecting others from infection. However, concerns have been raised regarding the pandemic´s impact and associated containment measures (e.g. curfew, lockdown) on nonâ€COVIDâ€19â€related acute medical diseases. OBJECTIVES: To investigate changes in the incidence of pulmonary embolism (PE) during the COVIDâ€19 pandemic compared to the period prior to the pandemic and reference periods in previous years. METHODS: In this singleâ€center study, we explored all diagnostic imaging tests performed for suspected PE between week 1â€17 of the years 2018, 2019, and 2020. Incidence of PE (i.e. primary outcome) was analyzed. Secondary outcomes included number of imaging tests for suspected PE. RESULTS: Compared to week 1â€11, 2020, an abrupt decline in PE diagnosis (mean weekly rate: 5.2 [95%CI: 3.8â€6.6] vs. 1.8 [0.0â€3.6]) and imaging tests (32.5 [27.5â€37.6] vs. 17.3 [11.6â€23.1]) was observed from week 12, with beginning of the containment measures and public lockdown in Austria. Compared to week 12â€17 of 2018 and 2019, PE incidence and imaging tests were similarly decreased from 5.3 [3.6â€7.1] to 1.8 [0.0â€3.6] and 31.5 [27.1â€35.9] to 17.3 [11.6â€23.1]), respectively. The median (IQR) sPESI score of PE patients during the pandemic was higher than in all other PE patients (3 [1â€3] vs. 1 [0â€2]; p=0.002). CONCLUSION: Our study demonstrates that the Covidâ€19 pandemic has an impact on nonâ€COVIDâ€19â€related acute diseases as shown by the decline in incidence of PE and imaging procedures for diagnostic workâ€up. Further studies from other hospitals are needed to confirm our findings.
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