Selected article for: "expression level and target expression level"
Author: Jing Qi; Yang Zhou; Jiao Hua; Liying Zhang; Jialin Bian; Beibei Liu; Zicen Zhao; Shuilin Jin
Title: The scRNA-seq expression profiling of the receptor ACE2 and the cellular protease TMPRSS2 reveals human organs susceptible to COVID-19 infection
  • Document date: 2020_4_18
    • ID: grvc7pnt_13
    Snippet: As the TMPRSS2 is a key protease to help the SARS-CoV-2 enter the target cells, and the expression level of TMPRSS2 implies the sensitivity of the cell to COVID-19 infection. Therefore, the susceptible organs were sorted into three groups by the ratios of TMPRSS2-expressed cells. In details, the cells with TMPRSS2-expressed ratio greater 20% are defined as level 1, which is at the highest risk; the cells with ratio more than 5% and less than 20% .....
    Document: As the TMPRSS2 is a key protease to help the SARS-CoV-2 enter the target cells, and the expression level of TMPRSS2 implies the sensitivity of the cell to COVID-19 infection. Therefore, the susceptible organs were sorted into three groups by the ratios of TMPRSS2-expressed cells. In details, the cells with TMPRSS2-expressed ratio greater 20% are defined as level 1, which is at the highest risk; the cells with ratio more than 5% and less than 20% are level 2, which means a higher risk; the rest are level 3, an existing risk of infection.

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