Author: Jing Qi; Yang Zhou; Jiao Hua; Liying Zhang; Jialin Bian; Beibei Liu; Zicen Zhao; Shuilin Jin
Title: The scRNA-seq expression profiling of the receptor ACE2 and the cellular protease TMPRSS2 reveals human organs susceptible to COVID-19 infection Document date: 2020_4_18
ID: grvc7pnt_13
Snippet: As the TMPRSS2 is a key protease to help the SARS-CoV-2 enter the target cells, and the expression level of TMPRSS2 implies the sensitivity of the cell to COVID-19 infection. Therefore, the susceptible organs were sorted into three groups by the ratios of TMPRSS2-expressed cells. In details, the cells with TMPRSS2-expressed ratio greater 20% are defined as level 1, which is at the highest risk; the cells with ratio more than 5% and less than 20% .....
Document: As the TMPRSS2 is a key protease to help the SARS-CoV-2 enter the target cells, and the expression level of TMPRSS2 implies the sensitivity of the cell to COVID-19 infection. Therefore, the susceptible organs were sorted into three groups by the ratios of TMPRSS2-expressed cells. In details, the cells with TMPRSS2-expressed ratio greater 20% are defined as level 1, which is at the highest risk; the cells with ratio more than 5% and less than 20% are level 2, which means a higher risk; the rest are level 3, an existing risk of infection.
Search related documents:
Co phrase search for related documents- cell ratio and great ratio cell: 1
- cell ratio and high risk: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12
- cell ratio and ratio cell: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76
- cell ratio and target cell: 1, 2, 3, 4, 5
- cell sensitivity and high risk: 1, 2, 3, 4, 5
- cell sensitivity and infection cell sensitivity: 1, 2
- cell sensitivity and ratio cell: 1
- cell sensitivity and target cell: 1, 2
- exist risk and high risk: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19
- exist risk and infection exist risk: 1, 2, 3, 4, 5
- expression level and high risk: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18
- expression level and key protease: 1
- expression level and ratio cell: 1, 2, 3, 4, 5, 6
- expression level and susceptible organ: 1
- expression level and target cell: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10
- great ratio cell and ratio cell: 1
- high risk and ratio cell: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12
- high risk and susceptible organ: 1, 2, 3, 4
- high risk and target cell: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12
Co phrase search for related documents, hyperlinks ordered by date