Author: Hazel Stewart; Katherine Brown; Adam M. Dinan; Nerea Irigoyen; Eric J. Snijder; Andrew E. Firth
Title: The transcriptional and translational landscape of equine torovirus Document date: 2018_4_7
ID: mozfm5ds_11
Snippet: Ribosome profiling (Ribo-seq) conducted in tandem with the RNA-seq indicated 124 ribosomes were actively translating within the so-called 5' UTR. Further analysis 125 confirmed the existence of two novel ORFs in this region, which are conserved in all 126 torovirus genome sequences analysed to date. The specific function(s) of these 127 proteins will be the topic of future work. Together, these results provide an overview 128 of the transcription.....
Document: Ribosome profiling (Ribo-seq) conducted in tandem with the RNA-seq indicated 124 ribosomes were actively translating within the so-called 5' UTR. Further analysis 125 confirmed the existence of two novel ORFs in this region, which are conserved in all 126 torovirus genome sequences analysed to date. The specific function(s) of these 127 proteins will be the topic of future work. Together, these results provide an overview 128 of the transcriptional and translational events that accompany infection by this wide-129 ranging pathogen. 130
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