Author: Hotez, Peter J.; Corry, David B.; Bottazzi, Maria Elena
Title: COVID-19 vaccine design: the Janus face of immune enhancement Cord-id: npzri0rh Document date: 2020_4_28
ID: npzri0rh
Snippet: Previous work on severe acute respiratory syndrome coronavirus (SARS-CoV) vaccines identified cellular immunopathology and antibody-dependent enhancement as potential safety issues. We discuss the implications of these findings for COVID-19 vaccine development and our approach to optimizing for safety and efficacy.
Document: Previous work on severe acute respiratory syndrome coronavirus (SARS-CoV) vaccines identified cellular immunopathology and antibody-dependent enhancement as potential safety issues. We discuss the implications of these findings for COVID-19 vaccine development and our approach to optimizing for safety and efficacy.
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