Author: Wang, Chunyan; Li, Wentao; Drabek, Dubravka; Okba, Nisreen M. A.; van Haperen, Rien; Osterhaus, Albert D. M. E.; van Kuppeveld, Frank J. M.; Haagmans, Bart L.; Grosveld, Frank; Bosch, Berend-Jan
Title: A human monoclonal antibody blocking SARS-CoV-2 infection Cord-id: 9n7bkayx Document date: 2020_5_4
ID: 9n7bkayx
Snippet: The emergence of the novel human coronavirus SARS-CoV-2 in Wuhan, China has caused a worldwide epidemic of respiratory disease (COVID-19). Vaccines and targeted therapeutics for treatment of this disease are currently lacking. Here we report a human monoclonal antibody that neutralizes SARS-CoV-2 (and SARS-CoV) in cell culture. This cross-neutralizing antibody targets a communal epitope on these viruses and may offer potential for prevention and treatment of COVID-19.
Document: The emergence of the novel human coronavirus SARS-CoV-2 in Wuhan, China has caused a worldwide epidemic of respiratory disease (COVID-19). Vaccines and targeted therapeutics for treatment of this disease are currently lacking. Here we report a human monoclonal antibody that neutralizes SARS-CoV-2 (and SARS-CoV) in cell culture. This cross-neutralizing antibody targets a communal epitope on these viruses and may offer potential for prevention and treatment of COVID-19.
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