Author: van Ewijk, Bart E.; van der Zalm, Marieke M.; Wolfs, Tom F.W.; van der Ent, Cornelis K.
Title: Viral respiratory infections in cystic fibrosis Cord-id: ntgu17ng Document date: 2005_6_17
ID: ntgu17ng
Snippet: Viral respiratory infections in CF patients are associated with an increase in morbidity at short and long term. Viral infections have a greater impact on CF patients compared to non-CF controls. They result in increased respiratory symptoms, deterioration of Shwachman and radiological scores, prolonged hospitalizations, a persistent decrease of pulmonary function, increased use of antibiotics and a higher frequency of exacerbations at follow-up. In addition, interaction between viruses and bact
Document: Viral respiratory infections in CF patients are associated with an increase in morbidity at short and long term. Viral infections have a greater impact on CF patients compared to non-CF controls. They result in increased respiratory symptoms, deterioration of Shwachman and radiological scores, prolonged hospitalizations, a persistent decrease of pulmonary function, increased use of antibiotics and a higher frequency of exacerbations at follow-up. In addition, interaction between viruses and bacteria in CF is suggested. Some studies observe increased new bacterial colonization and raised antipseudomonal antibodies in episodes of viral respiratory infections. Experimental data suggest that increased virus replication, impaired specific anti-bacterial defense and increased adherence of bacteria play a role in the pathogenesis of viral respiratory infections in CF. Further knowledge about the role of viruses and interaction with bacteria in CF lung disease might result in new therapeutic strategies to improve prognosis of CF patients.
Search related documents:
Co phrase search for related documents- active vaccination and long short: 1, 2, 3
- active vaccination and long short term: 1, 2, 3
- active vaccination and lung disease: 1
- active vaccination and lung infection: 1
- adenovirus parainfluenzavirus and lung function: 1
- long short and low frequency: 1, 2, 3, 4, 5, 6, 7
- long short and low threshold: 1, 2
- long short and lung disease: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15
- long short and lung function: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11
- long short and lung infection: 1, 2, 3, 4, 5, 6
- long short term and low frequency: 1, 2, 3, 4
- long short term and low threshold: 1
- long short term and lung disease: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13
- long short term and lung function: 1, 2, 3, 4, 5, 6, 7
- long short term and lung infection: 1, 2, 3, 4, 5
Co phrase search for related documents, hyperlinks ordered by date