Author: Xavier Hernandez-Alias; Martin Schaefer; Luis Serrano
Title: Translational adaptation of human viruses to the tissues they infect Document date: 2020_4_7
ID: 0rk2dw4e_27
Snippet: Overall, we determine that the tropism-specific adaptation of viruses is specifically pronounced among early proteins. However, later in infection, the tRNA pool of the host cells is reprogrammed to favor the expression of late viral genes, reproducing previous findings of HIV1 infection and extending the mechanism to dsDNA-based viruses such as human cytomegaloviruses and human simplex viruses......
Document: Overall, we determine that the tropism-specific adaptation of viruses is specifically pronounced among early proteins. However, later in infection, the tRNA pool of the host cells is reprogrammed to favor the expression of late viral genes, reproducing previous findings of HIV1 infection and extending the mechanism to dsDNA-based viruses such as human cytomegaloviruses and human simplex viruses.
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