Author: Chung, Mina K.; Zidar, David A.; Bristow, Michael R.; Cameron, Scott J.; Chan, Timothy; Harding, Clifford V.; Kwon, Deborah H.; Singh, Tamanna; Tilton, John C.; Tsai, Emily J.; Tucker, Nathan R.; Barnard, John; Loscalzo, Joseph
Title: COVID-19 and Cardiovascular Disease: From Bench to Bedside Cord-id: oeudi6lr Document date: 2021_4_16
ID: oeudi6lr
Snippet: A pandemic of historic impact, coronavirus disease 2019 (COVID-19) has potential consequences on the cardiovascular health of millions of people who survive infection worldwide. Severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2), the etiologic agent of COVID-19, can infect the heart, vascular tissues, and circulating cells through ACE2 (angiotensin-converting enzyme 2), the host cell receptor for the viral spike protein. Acute cardiac injury is a common extrapulmonary manifestation of
Document: A pandemic of historic impact, coronavirus disease 2019 (COVID-19) has potential consequences on the cardiovascular health of millions of people who survive infection worldwide. Severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2), the etiologic agent of COVID-19, can infect the heart, vascular tissues, and circulating cells through ACE2 (angiotensin-converting enzyme 2), the host cell receptor for the viral spike protein. Acute cardiac injury is a common extrapulmonary manifestation of COVID-19 with potential chronic consequences. This update provides a review of the clinical manifestations of cardiovascular involvement, potential direct SARS-CoV-2 and indirect immune response mechanisms impacting the cardiovascular system, and implications for the management of patients after recovery from acute COVID-19 infection.
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