Author: Nishiura, Hiroshi; Mizumoto, Kenji
Title: Epidemiological Determinants of Successful Vaccine Development Cord-id: e278thvo Document date: 2013_2_21
ID: e278thvo
Snippet: Epidemiological determinants of successful vaccine development were explored using measurable biological variables including antigenic stability and requirement of T-cell immunity. Employing a logistic regression model, we demonstrate that a high affinity with blood and immune cells and pathogen interactions (e.g. interference) would be the risk factors of failure for vaccine development.
Document: Epidemiological determinants of successful vaccine development were explored using measurable biological variables including antigenic stability and requirement of T-cell immunity. Employing a logistic regression model, we demonstrate that a high affinity with blood and immune cells and pathogen interactions (e.g. interference) would be the risk factors of failure for vaccine development.
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