Author: Gerry Killeen; Samson Kiware
Title: Why lockdown? Simplified arithmetic tools for decision-makers, health professionals, journalists and the general public to explore containment options for the novel coronavirus Document date: 2020_4_20
ID: io2f52kn_9
Snippet: As points of reference against which ongoing national containment campaigns may benchmark themselves, the epidemic was predicted to grow 59% bigger each week at the outset and shrink by 48% each week once rigorous lock down had been in place for several weeks. Note, however, that even these alarming projections for the rate of expansion of the epidemic and the rate of contraction required to contain it may under-represent the scale of the challen.....
Document: As points of reference against which ongoing national containment campaigns may benchmark themselves, the epidemic was predicted to grow 59% bigger each week at the outset and shrink by 48% each week once rigorous lock down had been in place for several weeks. Note, however, that even these alarming projections for the rate of expansion of the epidemic and the rate of contraction required to contain it may under-represent the scale of the challenge in real epidemics. For example, at the outset of the epidemic in China, numbers of confirmed cases doubled every week. 31, 79 Furthermore, subsequent analyses allowing for frequent carriage without overt symptoms indicate much higher viral reproduction rates than assumed in table 1, and suggest true doubling time for all cases may be less than 3 days. 65, 67 Interesting, almost exactly the same containment trajectory is predicted even if contact tracing and isolation is completely removed from the intervention package (Supplementary figure 1) , resulting in only 276 more cases and one more death. The explanation for this becomes apparent when one examines the trajectories of confirmed versus all cases: Even though the number of real cases never approaches an optimistically-assumed full testing capacity of 11,400 patients per week, half of all cases are never tested because they are asymptomatic and most of the remainder are only mildly symptomatic, so they get lost in the mass of other people who appear equally sick for unrelated to is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity.
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