Author: Hongzhou Lu; Jingwen Ai; Yinzhong Shen; Yang Li; Tao Li; Xian Zhou; Haocheng Zhang; Qiran Zhang; Yun Ling; Sheng Wang; Hongping Qu; Yuan Gao; Yingchuan Li; Kanglong Yu; Duming Zhu; Hecheng Zhu; Rui Tian; Mei Zeng; Qiang Li; Yuanlin Song; Xiangyang Li; Jinfu Xu; Jie Xu; Enqiang Mao; Bijie Hu; Xin Li; Lei Zhu; Wenhong Zhang
Title: A descriptive study of the impact of diseases control and prevention on the epidemics dynamics and clinical features of SARS-CoV-2 outbreak in Shanghai, lessons learned for metropolis epidemics prevention Document date: 2020_2_23
ID: dbzrd23n_60
Snippet: The proportion of severe and critically ill patients in Shanghai was significantly lower 313 than that in Wuhan. We consider the proportion of patients with severe illness to be a very 314 important indicator of the disease. First, regional mortality rate varies widely in the early 315 stages of the disease outbreak because it is affected by many factors, such as life support 316 equipment for critically ill patients and local medical conditions......
Document: The proportion of severe and critically ill patients in Shanghai was significantly lower 313 than that in Wuhan. We consider the proportion of patients with severe illness to be a very 314 important indicator of the disease. First, regional mortality rate varies widely in the early 315 stages of the disease outbreak because it is affected by many factors, such as life support 316 equipment for critically ill patients and local medical conditions. In the absence of effective 317 antiviral drugs, the proportion of critically ill patients depicts the natural course of the 318 disease better than the mortality rate. Second, because the final clinical outcome of 319 majority of the reported cases is typically unknown during a growing epidemic, dividing the 320 cumulative reported deaths by reported cases will underestimate the mortality rate early in 321 an epidemic [17] . We believe that the proportion of severe illness in Wuhan is biased 322 towards detecting severe cases, partly because diagnostic capacity is limited at the start 323 of an epidemic. Because of Shanghai's active surveillance, especially for suspected cases 324 with recent travel history to the affected region and close contacts, demonstrating by 325 shorter onset-administration interval and 4% asymptomatic patients on admission, 326
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