A globally available COVID-19 - Template for clinical imaging studies

Gabriel Alexander Salg; Maria Katharina Ganten; Matthias Baumhauer; Claus Peter Heussel; Jens Kleesiek

1122/1294), 10, 16, 17, 19 typically with bilateral lung involvement, 10,11,17,18 peripheral distribution 16,17,19,21 113 and ground-glass opacification of the lesions 10, [16] [17] [18] [19] 21 . Depending on the stage of the disease 114 consolidations 16-19,21 , intra-18,21 and interlobular 16-18,21 septal thickening, crazy paving pattern, [16] [17] [18] 115 spider web signs 16,18 and air bronchogram sign 17,19,21 were observed (Figure 1 , right). In contrast, pleural 116 effusion 16-19,21 and lymphadenopathy [16] [17] [18] [19] 21 were found rarely and do not seem to be typical for COVID-117 19 pneumonia. Although current evidence for COVID-19 pneumonia relies on data from preliminary 118 clinical studies and thus is most likely subjected to change over time, we illustrated that some clinical 119 symptoms and radiological findings were found more frequently than others, supporting a diagnosis 120 of COVID-19 pneumonia, whereas others seem to be very rare and support a consideration of other 121 differential diagnoses (Figure 1) . Nevertheless, or precisely because of it, these parameters were 122 included in the eCRF to enable a solid decision-making.