Author: MacMullan, Melanie A.; Ibrayeva, Albina; Trettner, Kylie; Deming, Laura; Das, Sudipta; Tran, Frances; Moreno, Jose Ricardo; Casian, Joseph G.; Chellamuthu, Prithivi; Kraft, Jeffrey; Kozak, Kenneth; Turner, Fred E.; Slepnev, Vladimir I.; Le Page, Lydia M.
Title: ELISA detection of SARS-CoV-2 antibodies in saliva Cord-id: ckjzr31j Document date: 2020_11_30
ID: ckjzr31j
Snippet: To facilitate containment of the COVID-19 pandemic currently active in the United States and across the world, options for easy, non-invasive antibody testing are required. Here we have adapted a commercially available, serum-based enzyme-linked immunosorbent assay (ELISA) for use with saliva samples, achieving 84.2% sensitivity and 100% specificity in a set of 149 clinical samples. This strategy will enable widespread, affordable testing for patients who experienced this disease, whilst minimiz
Document: To facilitate containment of the COVID-19 pandemic currently active in the United States and across the world, options for easy, non-invasive antibody testing are required. Here we have adapted a commercially available, serum-based enzyme-linked immunosorbent assay (ELISA) for use with saliva samples, achieving 84.2% sensitivity and 100% specificity in a set of 149 clinical samples. This strategy will enable widespread, affordable testing for patients who experienced this disease, whilst minimizing exposure risk for healthcare workers.
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