Author: Ming Zhong; Aijun Sun; Ting Xiao; Ge Yao; Ling Sang; Xia Zheng; Jinyan Zhang; Xuejuan Jin; Lei Xu; Wenlong Yang; Peng Wang; Kai Hu; Dingyu Zhang; Junbo Ge
Title: A Randomized, Single-blind, Group sequential, Active-controlled Study to evaluate the clinical efficacy and safety of a-Lipoic acid for critically ill patients with coronavirus disease 2019(COVID-19) Document date: 2020_4_21
ID: mvsnybbo_2
Snippet: α-Lipoic acid (ALA), as an antioxidant, has been confirmed to reduce systemic inflammatory response in patients with acute coronary syndromes, liver transplantation patients, and kidney-pancreas combined transplantation patients [21] [22] [23] [24] . Therefore, the aim of this study was to investigate whether ALA could alleviate systemic inflammatory response by reducing ROS production, thereby improve organ function and the prognosis of critica.....
Document: α-Lipoic acid (ALA), as an antioxidant, has been confirmed to reduce systemic inflammatory response in patients with acute coronary syndromes, liver transplantation patients, and kidney-pancreas combined transplantation patients [21] [22] [23] [24] . Therefore, the aim of this study was to investigate whether ALA could alleviate systemic inflammatory response by reducing ROS production, thereby improve organ function and the prognosis of critically ill patients with COVID-19.
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