Selected article for: "case number and fatality severity"
Author: Rosanna Asselta; Elvezia Maria Paraboschi; Alberto Mantovani; Stefano Duga
Title: ACE2 and TMPRSS2 variants and expression as candidates to sex and country differences in COVID-19 severity in Italy
  • Document date: 2020_4_2
    • ID: hrottr01_33
    Snippet: We are aware of the limitations of our study: first of all we focused our attention only to two candidate genes identified on the basis of their crucial role in viral infection and on the a priori probability that they might mediate sex-specific effects. A number of other X-linked genes (such as IL13, IL4, IL10, XIST, TLR7, FOXP3) and Y-linked genes (SRY, SOX9) may underlie sexually dimorphic immune responses. 30 Moreover, the number of non-genet.....
    Document: We are aware of the limitations of our study: first of all we focused our attention only to two candidate genes identified on the basis of their crucial role in viral infection and on the a priori probability that they might mediate sex-specific effects. A number of other X-linked genes (such as IL13, IL4, IL10, XIST, TLR7, FOXP3) and Y-linked genes (SRY, SOX9) may underlie sexually dimorphic immune responses. 30 Moreover, the number of non-genetic determinants of sex-biased severity and case fatality rates is huge and probably has to do not only with sex differences in both innate and adaptive immune responses, 6 but also with gender and cultural habits in different countries.

    Search related documents:
    Co phrase search for related documents
    • adaptive innate and case fatality rate: 1, 2
    • adaptive innate and crucial role: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23
    • adaptive innate and fatality rate: 1, 2
    • adaptive innate and immune response: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
    • adaptive innate and sex bias: 1, 2
    • adaptive innate and sex difference: 1, 2
    • adaptive innate immune response and crucial role: 1, 2
    • adaptive innate immune response and immune response: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
    • attention focus and crucial role: 1, 2, 3, 4
    • attention focus and immune response: 1, 2, 3, 4, 5, 6, 7
    • candidate gene and crucial role: 1
    • candidate gene and immune response: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11
    • case fatality rate and crucial role: 1, 2, 3, 4, 5, 6, 7, 8
    • case fatality rate and different country: 1, 2, 3, 4
    • case fatality rate and fatality rate: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
    • case fatality rate and immune response: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24
    • case fatality rate and sex bias: 1
    • case fatality rate and sex difference: 1, 2, 3, 4
    • crucial role and different country: 1, 2, 3, 4