Author: Bruna GG Pinto; Antonio ER Oliveira; Youvika Singh; Leandro Jimenez; Andre NA Goncalves; Rodrigo LT Ogava; Rachel Creighton; Jean PS Peron; Helder I Nakaya
Title: ACE2 Expression is Increased in the Lungs of Patients with Comorbidities Associated with Severe COVID-19 Document date: 2020_3_27
ID: 2un9aggj_8
Snippet: Gene IDs were converted to gene symbols using the biomaRt R package [16, 17] , and disease IDs were converted to disease MeSH terms using the Entrez Programming Utilities to query the Entrez database provided by the National Center for Biotechnology Information. The data was then further filtered to retain disease MeSH terms relevant to reported clinical COVID-19 comorbidities [3] . Redundant terms were collapsed using fuzzy string matching. The .....
Document: Gene IDs were converted to gene symbols using the biomaRt R package [16, 17] , and disease IDs were converted to disease MeSH terms using the Entrez Programming Utilities to query the Entrez database provided by the National Center for Biotechnology Information. The data was then further filtered to retain disease MeSH terms relevant to reported clinical COVID-19 comorbidities [3] . Redundant terms were collapsed using fuzzy string matching. The final gene-disease data set was used to generate a network utilizing Gephi software where the nodes were genes and diseases, and the edge weight was determined by the number of analyzed papers containing the gene-disease combination [18] .
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