Selected article for: "age range and interquartile range"
Author: Jiatao Lu; Shufang Hu; Rong Fan; Zhihong Liu; Xueru Yin; Qiongya Wang; Qingquan Lv; Zhifang Cai; Haijun Li; Yuhai Hu; Ying Han; Hongping Hu; Wenyong Gao; Shibo Feng; Qiongfang Liu; Hui Li; Jian Sun; Jie Peng; Xuefeng Yi; Zixiao Zhou; Yabing Guo; Jinlin Hou
Title: ACP risk grade: a simple mortality index for patients with confirmed or suspected severe acute respiratory syndrome coronavirus 2 disease (COVID-19) during the early stage of outbreak in Wuhan, China
  • Document date: 2020_2_23
    • ID: eu3rry7p_4
    Snippet: Results: Of 577 patients with at least one post-admission evaluation, the median age was 55 years (interquartile range [IQR] , 39 -66); 254 (44.0%) were men; 22.8% (100/438) were severe pneumonia on admission, and 37.7% (75/199) patients were SARS-CoV-2 positive. The clinical, laboratory and radiological data were comparable between positive and negative SARS-CoV-2 patients. During a median follow-up of 8.4 days (IQR, 5.8 -12.0), 39 patients died.....
    Document: Results: Of 577 patients with at least one post-admission evaluation, the median age was 55 years (interquartile range [IQR] , 39 -66); 254 (44.0%) were men; 22.8% (100/438) were severe pneumonia on admission, and 37.7% (75/199) patients were SARS-CoV-2 positive. The clinical, laboratory and radiological data were comparable between positive and negative SARS-CoV-2 patients. During a median follow-up of 8.4 days (IQR, 5.8 -12.0), 39 patients died with a 12-day cumulative mortality of 8.7% (95% CI, 5.9% to 11.5%). A simple mortality risk index (called ACP index), composed of Age and C-reactive Protein, was developed. By applying the ACP index, patients were categorized into three grades. The 12-day cumulative mortality in grade three (age ≥ 60 years and CRP ≥ 34 mg/L) was 33.2% (95% CI, 19.8% to 44.3%), which was significantly higher than those of grade two (age ≥ 60 years and CRP < 34 mg/L; age < 60 years and CRP ≥ 34 mg/L; 5.6% [95% CI, 0 to 11.3%]) and grade one (age < 60 years and CRP < 34 mg/L, 0%) (P <0.001), respectively.

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