Author: Qingyang Xu; Shomesh Chaudhuri; Danying Xiao; Andrew W Lo
Title: Bayesian Adaptive Clinical Trials for Anti-Infective Therapeutics during Epidemic Outbreaks Document date: 2020_4_14
ID: 20hk99h4_7
Snippet: Moreover, the cost of Type I versus Type II error can differ from therapy to therapy. A novel vaccine that could trigger a significant immune response such as a cytokine storm has a much higher cost of a Type I error than a medical device such as an air filtration system designed to destroy virions through intense ultraviolet light. Therefore, the appropriate statistical threshold for approval should depend on the specific therapy, as well as the.....
Document: Moreover, the cost of Type I versus Type II error can differ from therapy to therapy. A novel vaccine that could trigger a significant immune response such as a cytokine storm has a much higher cost of a Type I error than a medical device such as an air filtration system designed to destroy virions through intense ultraviolet light. Therefore, the appropriate statistical threshold for approval should depend on the specific therapy, as well as the circumstances of the current burden of disease.
Search related documents:
Co phrase search for related documents- current burden and disease current burden: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- current burden and high cost: 1
- current burden and immune response: 1
- cytokine storm and disease current burden: 1
- cytokine storm and high cost: 1, 2
- cytokine storm and immune response: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- cytokine storm and novel vaccine: 1, 2, 3, 4, 5, 6, 7, 8
- cytokine storm and specific therapy: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18
- cytokine storm immune response and immune response: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- cytokine storm immune response and specific therapy: 1
- disease current burden and immune response: 1
- high cost and immune response: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11
- high cost and medical device: 1, 2, 3, 4
- high cost and novel vaccine: 1, 2
- high cost and specific therapy: 1, 2
- immune response and novel vaccine: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- immune response and specific therapy: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- medical device and specific therapy: 1
Co phrase search for related documents, hyperlinks ordered by date