Selected article for: "cell expression and co expression"
Author: Weishan Huang; Sabrina Solouki; Chavez Carter; Song-Guo Zheng; Avery August
Title: Beyond type 1 regulatory T cells: co-expression of LAG3 and CD49b in IL-10-producing T cell lineages
  • Document date: 2018_6_30
    • ID: ivyp5cgz_33
    Snippet: Our data presented in this report demonstrated that, in contrast to previously reported [15] , 289 co-expression of LAG3 and CD49b is not an exclusive cell surface signature of Foxp3 -IL-10 high 290 Tr1 cells in human and mouse. In addition, we find that the IL-10-producing LAG3 + CD49b + T cell 291 population is composed of Foxp3 + CD4 + , Foxp3 -CD4 + , and CD8 + T cell subsets, and this 292 composition varies depending on disease conditions an.....
    Document: Our data presented in this report demonstrated that, in contrast to previously reported [15] , 289 co-expression of LAG3 and CD49b is not an exclusive cell surface signature of Foxp3 -IL-10 high 290 Tr1 cells in human and mouse. In addition, we find that the IL-10-producing LAG3 + CD49b + T cell 291 population is composed of Foxp3 + CD4 + , Foxp3 -CD4 + , and CD8 + T cell subsets, and this 292 composition varies depending on disease conditions and anatomical locations of the cells. The 293 significance of this work is emphasized due to the importance of identifying Foxp3 -Tr1 cells, 294

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