Selected article for: "age disease severity and disease severity"

Author: Chanaka N Kahathuduwa; Chathurika S Dhanasekara; Shao-Hua Chin
Title: Case fatality rate in COVID-19: a systematic review and meta-analysis
  • Document date: 2020_4_6
  • ID: dcf6bl8f_31
    Snippet: In conclusion, after correcting for publication bias, COVID-19 associated overall rates of 294 requirement for hospitalization, intensive care and case fatality could be as high as 26%, 16% 295 and 7.4% respectively. This underscores the importance of strict adherence to preventive 296 measures, case detection, surveillance and reporting. Hypertension; fever and dyspnea at 297 presentation; and elevated CRP seem to predict increased disease sever.....
    Document: In conclusion, after correcting for publication bias, COVID-19 associated overall rates of 294 requirement for hospitalization, intensive care and case fatality could be as high as 26%, 16% 295 and 7.4% respectively. This underscores the importance of strict adherence to preventive 296 measures, case detection, surveillance and reporting. Hypertension; fever and dyspnea at 297 presentation; and elevated CRP seem to predict increased disease severity, while increasing age 298 and elevated LDH seem to consistently predict severity and case fatality. These risk factors 299 should inform clinicians to define endophenotypes possessing a greater risk. author/funder, who has granted medRxiv a license to display the preprint in perpetuity.

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