Selected article for: "clinical outcome and illness onset"

Author: Wen Zhao; Shikai Yu; Xiangyi Zha; Ning Wang; Qiumei Pang; Tongzeng Li; Aixin Li
Title: Clinical characteristics and durations of hospitalized patients with COVID-19 in Beijing: a retrospective cohort study
  • Document date: 2020_3_17
  • ID: n0uwy77g_26
    Snippet: The duration of the illness onset to hospital admission is an important factor in the spreading of virus infection. The sooner patients are hospitalized and treated, the less spreading there will be. Previous studies reported that the duration of the illness onset to hospital admission in the early stage of this outbreak was 7 to 12.5 days. 2, 3, 5 In the present study, the time from the symptom onset to hospital admission was significantly short.....
    Document: The duration of the illness onset to hospital admission is an important factor in the spreading of virus infection. The sooner patients are hospitalized and treated, the less spreading there will be. Previous studies reported that the duration of the illness onset to hospital admission in the early stage of this outbreak was 7 to 12.5 days. 2, 3, 5 In the present study, the time from the symptom onset to hospital admission was significantly shorter (5 days, IQR 3-6 days), which should be attributed to the increased awareness of the public on the epidemic and the daily public-wide educational campaigns on precautionary measures against exposure to SARS-Cov-2. It is equivocal that whether longer duration between symptom onset to hospital admission is associated with clinical outcome of patients. Huang et al. 2 did not find a difference of this duration between ICU and non-ICU patients, however, Wang et al. 5 investigated more patients and revealed that patients admitted to ICU had longer duration (8 vs. 6 days, P=0.009). In the present study, we also observed a longer duration in severe patients versus non-severe patients (supplementary files). This may be attributed to that longer pre-hospital duration may delay the treatment thus lead to unfavorable outcomes.

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