Author: Zijun Wang; Qi Zhou; Chenglin Wang; Qianling Shi; Shuya Lu; Yanfang Ma; Xufei Luo; Yangqin Xun; Weiguo Li; Muna Baskota; Yinmei Yang; Hui Zhai; Toshio Fukuoka; Hyeong Sik Ahn; Myeong Soo Lee; Zhengxiu Luo; Enmei Liu; Yaolong Chen
Title: Clinical Characteristics of Children with COVID-19: A Rapid Review and Meta-Analysis Document date: 2020_4_17
ID: jsjxdmi2_23
Snippet: Chinese CDC also pointed out that 889 (1%) patients with COVID-19 were asymptomatic (82); in our study, about 19% of children were completely asymptomatic, which is higher than the average level of the whole patient significantly. A study of asymptomatic infections with COVID-19 also showed that 29.2% of cases showed normal CT image and had no symptoms during hospitalization. What's more, these cases were younger (median age: 14.0 years; P=0.012).....
Document: Chinese CDC also pointed out that 889 (1%) patients with COVID-19 were asymptomatic (82); in our study, about 19% of children were completely asymptomatic, which is higher than the average level of the whole patient significantly. A study of asymptomatic infections with COVID-19 also showed that 29.2% of cases showed normal CT image and had no symptoms during hospitalization. What's more, these cases were younger (median age: 14.0 years; P=0.012) than the rest.(89) Of children with COVID-19, 83% had other family members infected. The majority of asymptomatic children in family clusters were confirmed after a positive nucleic acid test, which was conducted because of the close contact to infected family members. It seems that family cluster in children were more likely to be tested than adults. So, we suspect whether asymptomatic children are really asymptomatic or are still in the incubation period. Another explanation could be that only symptomatic cases transmit; So, adults without symptoms are seldom diagnosed, while children without symptoms (who had not that many any other contacts during the holiday season than their family members) get diagnosed anyway because of the obvious exposure.
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