Author: Roshan Kumar; Helianthous Verma; Nirjara Singhvi; Utkarsh Sood; Vipin Gupta; Mona Singh; Rashmi Sharma; Princy Hira; Shekhar Nagar; Chandni Talwar; Namita Nayyar; Shailly Anand; Charu Dogra Rawat; Mansi Verma; Ram Kishan Negi; Yogendra Singh; Rup Lal
Title: Comparative Genomic Analysis of Rapidly Evolving SARS CoV-2 Viruses Reveal Mosaic Pattern of Phylogeographical Distribution Document date: 2020_3_30
ID: eqwxkwqa_23
Snippet: The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.03.25.006213 doi: bioRxiv preprint oronasopharynges or lungs, while two of them were isolated from faeces suggesting both 186 respiratory and gastrointestinal connection of SARS-CoV-2 (Table 1) . No information of the 187 source of isolation of the remaining isolates is available. The average genome size and GC 188 content were found to be 2.....
Document: The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.03.25.006213 doi: bioRxiv preprint oronasopharynges or lungs, while two of them were isolated from faeces suggesting both 186 respiratory and gastrointestinal connection of SARS-CoV-2 (Table 1) . No information of the 187 source of isolation of the remaining isolates is available. The average genome size and GC 188 content were found to be 29879 ± 26.6 bp and 37.99 ± 0.018%, respectively. All these isolates 189 were found to harbor 9 open reading frames coding for ORF1a (13218 bp) and ORF1b (7788 190 bp) polyproteins, surface glycoprotein or S-protein (3822 bp), ORF3a protein (828 bp Our analysis revealed that strains of human infecting SARS-CoV-2 are novel and highly 201 identical (>99.9%). A recent study established the closest neighbor of SARS-CoV-2 as SARSr-202
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