Selected article for: "binding affinity and homology modeling"

Author: Xiaoqiang Huang; Robin Pearce; Yang Zhang
Title: Computational Design of Peptides to Block Binding of the SARS-CoV-2 Spike Protein to Human ACE2
  • Document date: 2020_3_31
  • ID: imkeghfd_18
    Snippet: At the very beginning of the outbreak of SARS-CoV-2, to determine its relative infectivity, many computational studies were performed to compare the binding affinity of SARS-CoV-2 RBD for hACE2 with that of SARS-CoV RBD for hACE2 based on homology modeling structures; all these studies came up with the conclusion that SARS-CoV-2 showed much weaker binding affinity to hACE2 than SARS-CoV and SARS-CoV-2 might not be as infectious as SARS-CoV 32-34 .....
    Document: At the very beginning of the outbreak of SARS-CoV-2, to determine its relative infectivity, many computational studies were performed to compare the binding affinity of SARS-CoV-2 RBD for hACE2 with that of SARS-CoV RBD for hACE2 based on homology modeling structures; all these studies came up with the conclusion that SARS-CoV-2 showed much weaker binding affinity to hACE2 than SARS-CoV and SARS-CoV-2 might not be as infectious as SARS-CoV 32-34 .

    Search related documents:
    Co phrase search for related documents
    • bind affinity and homology modeling: 1, 2, 3
    • bind affinity and homology modeling structure: 1
    • bind affinity and SARS RBD bind affinity: 1, 2, 3, 4, 5
    • bind affinity and weak bind affinity: 1
    • computational study and homology modeling: 1, 2
    • computational study and homology modeling structure: 1
    • computational study and SARS outbreak: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19
    • homology modeling and SARS outbreak: 1, 2, 3