Selected article for: "exact test and multiple testing"
Author: Kevin Dick; Kyle K Biggar; James R Green
Title: Computational Prediction of the Comprehensive SARS-CoV-2 vs. Human Interactome to Guide the Design of Therapeutics
  • Document date: 2020_3_31
    • ID: dxabs45r_27
    Snippet: To determine which cellular pathways may be targeted by SARS-CoV-2, PANTHER Gene Ontology (GO) enrichment analysis was applied to all 225 human proteins predicted to interact with SARS-COV-2 proteins. The molecular function, biological pathway, and cellular pathway p-values were determined with the Fisher's Exact test implemented in the PANTHER Go software [12] . P-Values were corrected for multiple testing using the False Discovery Rate (FDR) me.....
    Document: To determine which cellular pathways may be targeted by SARS-CoV-2, PANTHER Gene Ontology (GO) enrichment analysis was applied to all 225 human proteins predicted to interact with SARS-COV-2 proteins. The molecular function, biological pathway, and cellular pathway p-values were determined with the Fisher's Exact test implemented in the PANTHER Go software [12] . P-Values were corrected for multiple testing using the False Discovery Rate (FDR) method [17] and significant terms were identified at a threshold of 0.05.

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