Selected article for: "initiation complex and ribosomal subunit"
Author: Sneha Rath; Eliza Prangley; Jesse Donovan; Kaitlin Demarest; Yigal Meir; Ned Wingreen; Alexei Korennykh
Title: Concerted 2-5A-Mediated mRNA Decay and Transcription Reprogram Protein Synthesis in dsRNA Response
  • Document date: 2018_12_4
    • ID: ng5c7xai_9
    Snippet: To examine the initiation complex more completely, we performed mass spectrometry (MS) of proteins that co-purify with eIF4E (Fig. S2 ). This analysis detected ribosomal proteins from the small subunit, translation initiation factors and poly-A binding proteins, but not proteins from the large ribosomal subunit, as expected due to polysome run off. The identified components did not change in response to 2-5A ( Fig. 2E ; Table S1 ), indicating 2.....
    Document: To examine the initiation complex more completely, we performed mass spectrometry (MS) of proteins that co-purify with eIF4E (Fig. S2 ). This analysis detected ribosomal proteins from the small subunit, translation initiation factors and poly-A binding proteins, but not proteins from the large ribosomal subunit, as expected due to polysome run off. The identified components did not change in response to 2-5A ( Fig. 2E ; Table S1 ), indicating 2-5AMD does not block the cap-binding complex and capmediated loading of the small ribosomal subunit.

    Search related documents:
    Co phrase search for related documents
    • bind protein and mass spectrometry: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11
    • bind protein and MS mass spectrometry: 1, 2, 3
    • bind protein and poly bind protein: 1, 2, 3
    • bind protein and ribosomal protein: 1, 2
    • bind protein and ribosomal subunit: 1, 2, 3, 4
    • bind protein and small ribosomal subunit: 1, 2, 3
    • cap bind and mass spectrometry: 1
    • cap bind and ribosomal protein: 1
    • cap bind complex and mass spectrometry: 1
    • cap bind complex and ribosomal protein: 1
    • identify component and mass spectrometry: 1, 2
    • identify component and MS mass spectrometry: 1, 2
    • initiation complex and mass spectrometry: 1, 2, 3
    • initiation complex and ribosomal protein: 1
    • initiation complex and ribosomal subunit: 1, 2, 3, 4, 5, 6, 7, 8
    • initiation complex and small ribosomal subunit: 1
    • large ribosomal subunit and ribosomal protein: 1
    • large ribosomal subunit and ribosomal subunit: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15
    • large ribosomal subunit and small ribosomal subunit: 1, 2, 3, 4