Author: Jinfang Yu; Shuyuan Qiao; Runyu Guo; Xinquan Wang
Title: Cryo-EM structures of HKU2 and SADS-CoV spike glycoproteins and insights into coronavirus evolution Document date: 2020_2_24
ID: 25va2cvt_34
Snippet: The HKU2 and SADS-CoV CTD structure have a one-layer core consisting of a 388 twisted five-stranded antiparallel β sheet. Interestingly, ï¢-coronavirus CTDs also have 389 the similar one-layer core structure and three strictly conserved disulfide bonds are also 390 present in the core of HKU2 CTD. Currently, all identified receptor-binding motif of ï¢-391 coronavirus CTDs are within an inserted domain between two stands of the core sheet, 392 .....
Document: The HKU2 and SADS-CoV CTD structure have a one-layer core consisting of a 388 twisted five-stranded antiparallel β sheet. Interestingly, ï¢-coronavirus CTDs also have 389 the similar one-layer core structure and three strictly conserved disulfide bonds are also 390 present in the core of HKU2 CTD. Currently, all identified receptor-binding motif of ï¢-391 coronavirus CTDs are within an inserted domain between two stands of the core sheet, 392 author/funder. All rights reserved. No reuse allowed without permission.
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