Analysis clinical features of COVID-19 infection in secondary epidemic area and report potential biomarkers in evaluation

Weiping Ji; Gautam Bishnu; Zhenzhai Cai; Xian Shen

According to a report from the main epidemic area, COVID-19-infected patients had limited lung lesions at the early stage of onset. CT showed multiple lesions and rarely single lesions in the lungs. CT findings appeared as localized small patches, sub-segmented or large ground glass shadows. Local leaflets were widely spaced and were with or without thickening. Progressive CT showed increased lesions, with some expanded lesions, and multiple lung lobes were involved; the density of the lesions increased, and irregular, wedge-shaped or fan-shaped consolidations of varying sizes and degrees within the lesions appeared. Mutated shadows or strip shadows coexisted. Diffuse lung lesions can be seen on CT in severe patients, with consolidation as the primary cause, in addition to ground glass shadows and multiple fiber strand shadows; in a few severe cases, "white lung" manifestations appeared when most of the lungs were affected, and an air bronchus sign was present [9] [10] [11] [12] . The results of imaging examinations of 33 patients in the secondary epidemic area collected in this study were similar to those reported in the main epidemic area, so no further explanation is given in the article.