Author: Asiedu Ebenezer
Title: Designing Effective small interfering RNA for Post-Transcriptional Silencing of Human GREM1: A Comprehensive Bioinformatics Approach Document date: 2020_1_24
ID: j99qg2a0_33
Snippet: The loop specific probability profiles were generated to further evaluate the target site availability (Figure 4) . The loop specific profiles represent the probability that a particular target site is not involved in hairpin, interior, bulge or multi-branched folds. The target sites for siRNA-6, siRNA-7 and siRNA-47 were predicted to be available. The target site for siRNA-47 (position 519-537) was not available for binding (Figure 1b) . Moreove.....
Document: The loop specific probability profiles were generated to further evaluate the target site availability (Figure 4) . The loop specific profiles represent the probability that a particular target site is not involved in hairpin, interior, bulge or multi-branched folds. The target sites for siRNA-6, siRNA-7 and siRNA-47 were predicted to be available. The target site for siRNA-47 (position 519-537) was not available for binding (Figure 1b) . Moreover, the site was predicted to form an interior loop (Figure 4c ).
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