Author: Christine Dahlke; Jasmin Heidepriem; Robin Kobbe; Rene Santer; Till Koch; Anahita Fathi; My L. Ly; Stefan Schmiedel; Peter H. Seeberger; Marylyn M. Addo; Felix F. Loeffler
Title: Distinct early IgA profile may determine severity of COVID-19 symptoms: an immunological case series Document date: 2020_4_17
ID: icl1t9d6_34
Snippet: We detected an early and defined IgA response in patient #2 who had a very mild course of disease. In addition, our patient #4 (mild/moderate course of disease, no hospitalization, see Supporting Information Figures S1 & S2) also showed an early IgA response. IgA is considered a major effector molecule involved in defense mechanisms against viruses and infections with respiratory viruses can induce efficient IgA responses in secretions as well as.....
Document: We detected an early and defined IgA response in patient #2 who had a very mild course of disease. In addition, our patient #4 (mild/moderate course of disease, no hospitalization, see Supporting Information Figures S1 & S2) also showed an early IgA response. IgA is considered a major effector molecule involved in defense mechanisms against viruses and infections with respiratory viruses can induce efficient IgA responses in secretions as well as in sera. Our data suggest that IgA antibodies are valuable diagnostic markers that show All rights reserved. No reuse allowed without permission.
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