Author: Alexa C. Robitaille; Elise Caron; Nicolas Zucchini; Espérance Mukawera; Damien Adam; Mélissa K. Mariani; Anaïs Gélinas; Audray Fortin; Emmanuelle Brochiero; Nathalie Grandvaux
Title: DUSP1 regulates apoptosis and cell migration, but not the JIP1-protected cytokine response, during Respiratory Syncytial Virus and Sendai Virus infection Document date: 2017_7_13
ID: jzzhpw7h_25
Snippet: As such, DUSP1 has been extensively shown to negatively regulate the innate immune antibacterial defense and the cellular response to allergens 66, 67 . In these contexts, DUSP1 mainly inhibits proinflammatory cytokine expression 40, [68] [69] [70] [71] [72] [73] . The role of DUSP1 in the innate response to virus infection is far less known and, to our knowledge, was not previously assessed in the context of infection by RSV or SeV......
Document: As such, DUSP1 has been extensively shown to negatively regulate the innate immune antibacterial defense and the cellular response to allergens 66, 67 . In these contexts, DUSP1 mainly inhibits proinflammatory cytokine expression 40, [68] [69] [70] [71] [72] [73] . The role of DUSP1 in the innate response to virus infection is far less known and, to our knowledge, was not previously assessed in the context of infection by RSV or SeV.
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