Selected article for: "Cox regression and mechanical ventilation"
Author: Yi Yang; Jia Shi; Shuwang Ge; Shuiming Guo; Xue Xing; Yanan Wang; Anying Cheng; Qingquan Liu; Junhua Li; Yong Ning; Fan He; Gang Xu
Title: Effect of continuous renal replacement therapy on all-cause mortality in COVID-19 patients undergoing invasive mechanical ventilation: a retrospective cohort study
  • Document date: 2020_3_20
    • ID: nnlynjoy_24
    Snippet: We further conducted univariate and multivariate Cox proportional hazard regression analysis for all-cause mortality of COVID-19 patients undergoing invasive mechanical ventilation with CRRT. After adjusting the prognostic significance of clinical factors including age, sex, inflammatory factors, coagulation function, liver, and renal function, and cardiac function, we demonstrated that older age (aHR=1.112, P=0.025), higher levels of IL-1β (aHR.....
    Document: We further conducted univariate and multivariate Cox proportional hazard regression analysis for all-cause mortality of COVID-19 patients undergoing invasive mechanical ventilation with CRRT. After adjusting the prognostic significance of clinical factors including age, sex, inflammatory factors, coagulation function, liver, and renal function, and cardiac function, we demonstrated that older age (aHR=1.112, P=0.025), higher levels of IL-1β (aHR=1.292, P=0.012), IL-2 receptor (aHR=1.002, P=0.013), hs-cTNI (aHR=1.001, P=0.004), and NT-proBNP (aHR=1.256, P=0.008) were significantly associated with increased risk of all-cause mortality ( Table 3 ).

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