Author: Noam Shental; Shlomia Levy; Shosh Skorniakov; Vered Wuvshet; Yonat Shemer-Avni; Angel Porgador; Tomer Hertz
Title: Efficient high throughput SARS-CoV-2 testing to detect asymptomatic carriers Document date: 2020_4_20
ID: bby9hls2_8
Snippet: is the (which was not peer-reviewed) The copyright holder for this preprint . https://doi.org/10.1101/2020.04.14.20064618 doi: medRxiv preprint University Medical Center using a clinically approved COVID-19 PCR-based diagnostic protocol that included an RNA extraction stage. We tested P-BEST using four sets of 384 samples, each containing an increasing number of positive carriers ranging from two to five. We found that P-BEST was able to correctl.....
Document: is the (which was not peer-reviewed) The copyright holder for this preprint . https://doi.org/10.1101/2020.04.14.20064618 doi: medRxiv preprint University Medical Center using a clinically approved COVID-19 PCR-based diagnostic protocol that included an RNA extraction stage. We tested P-BEST using four sets of 384 samples, each containing an increasing number of positive carriers ranging from two to five. We found that P-BEST was able to correctly identify all positive carriers within these four sets of 384 samples using only 48 tests per set, providing an 8-fold increase in testing efficiency. Simulations demonstrated that the method can correctly identify up to 5/384 (1.3%) of carriers, with an average number of false positives that was less than 2.75, and an average number of false negatives that was less than 0.33.
Search related documents:
Co phrase search for related documents- average number and false negative average number: 1, 2
- average number and false positive: 1, 2, 3
- average number and false positive average number: 1, 2
- average number and increase number: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73
- average number and testing efficiency: 1, 2
- correctly identify and false negative: 1, 2, 3
- correctly identify and false positive: 1
- diagnostic protocol and false negative: 1, 2, 3, 4, 5
- diagnostic protocol and false positive: 1, 2
- diagnostic protocol and testing efficiency: 1, 2
- extraction stage and false negative: 1
- extraction stage and increase number: 1
- extraction stage and RNA extraction stage: 1, 2
- false negative and increase number: 1, 2, 3, 4
- false negative and positive carrier: 1, 2
- false negative and testing efficiency: 1, 2, 3, 4, 5, 6, 7, 8, 9
- false negative and testing efficiency increase: 1
- false positive and increase number: 1, 2, 3, 4, 5, 6, 7
- false positive and PCR base: 1
Co phrase search for related documents, hyperlinks ordered by date