Author: Xiaojun Li; Elena E. Giorgi; Manukumar Honnayakanahalli Marichann; Brian Foley; Chuan Xiao; Xiang-peng Kong; Yue Chen; Bette Korber; Feng Gao
Title: Emergence of SARS-CoV-2 through Recombination and Strong Purifying Selection Document date: 2020_3_22
ID: 7v5aln90_22
Snippet: All 43 CoV complete genome sequences were obtained from GenBank and GISAID (Global Initiative on Sharing All Influenza Data) (35, 36) , and were selected to be representative of the diversity. Pan_SL-CoV_GD/P1La sequence was generated by combining Pan_SL-CoV_GD/P1L (10) with some additional sequences from the NCBI BioProject database PRJNA5732983 (11, 37) to have a maximal coverage of the complete genome sequence for analysis. A new CoV sequence .....
Document: All 43 CoV complete genome sequences were obtained from GenBank and GISAID (Global Initiative on Sharing All Influenza Data) (35, 36) , and were selected to be representative of the diversity. Pan_SL-CoV_GD/P1La sequence was generated by combining Pan_SL-CoV_GD/P1L (10) with some additional sequences from the NCBI BioProject database PRJNA5732983 (11, 37) to have a maximal coverage of the complete genome sequence for analysis. A new CoV sequence from pangolin (EPI_ISL_410721) (38) was not inclued because that it became available after we had already completed the analyses in this study, and it was not as close to SARS-CoV-2 sequences and did not change the interpretation of our results. The whole genome sequences were first aligned using Clustal X2 (39) . The alignments for all coding regions were manually optimized based on the amino acid sequence alignment using SeaView 5.0.1. author/funder. All rights reserved. No reuse allowed without permission.
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