Author: Danielle E. Goodman; Carla D. Pretto; Tomas A. Krepostman; Kelly E. Carnahan; Katherine R. Spindler
Title: Enhanced replication of mouse adenovirus type 1 following virus-induced degradation of protein kinase R (PKR) Document date: 2019_3_21
ID: 9utbwy5r_43
Snippet: In summary, we demonstrated that PKR has an antiviral role during MAV-1 infection in 415 vitro, because when PKR is mutated, viral replication in MEFs is significantly higher compared 416 to wild type MEFs. Analysis of global PKR steady-state protein levels during infection showed containing 5% or 10% heat-inactivated fetal bovine serum (FBS), respectively, before use. 432.....
Document: In summary, we demonstrated that PKR has an antiviral role during MAV-1 infection in 415 vitro, because when PKR is mutated, viral replication in MEFs is significantly higher compared 416 to wild type MEFs. Analysis of global PKR steady-state protein levels during infection showed containing 5% or 10% heat-inactivated fetal bovine serum (FBS), respectively, before use. 432
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