Selected article for: "clostridium difficile and CMV infection"
Author: Chi Heem Wong; Kien Wei Siah; Andrew W Lo
Title: Estimating Probabilities of Success of Clinical Trials for Vaccines and Other Anti-Infective Therapeutics
  • Document date: 2020_4_14
    • ID: fnrm6a79_35
    Snippet: is the (which was not peer-reviewed) The copyright holder for this preprint When we classify the vaccines by the biological family of the infectious agent ( Figure 7a ), we see that reoviridae (e.g., rotavirus), rhabdoviridae (e.g., rabies), and hepadnaviridae (e.g., HBV) are the three biological families with the highest overall PoS for vaccines at 78.7%, (SE: 5.2%), 66.7% (SE: 7.5%), and 53.7% (SE: 3.6%), respectively. We have yet to see a vac.....
    Document: is the (which was not peer-reviewed) The copyright holder for this preprint When we classify the vaccines by the biological family of the infectious agent ( Figure 7a ), we see that reoviridae (e.g., rotavirus), rhabdoviridae (e.g., rabies), and hepadnaviridae (e.g., HBV) are the three biological families with the highest overall PoS for vaccines at 78.7%, (SE: 5.2%), 66.7% (SE: 7.5%), and 53.7% (SE: 3.6%), respectively. We have yet to see a vaccine for diseases caused by agents in the biological families of retroviridae (e.g., HIV), caliciviridae (e.g., norovirus), clostridiaceae (e.g., clostridium difficile), coronaviridae (e.g., SARS, MERS), herpesviridae (e.g., CMV infection), or togaviridae (e.g., chikungunya).

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