Author: Jinwei Ai; Junyan Gong; Limin Xing; Renjiao He; Fangtao Tian; Juan Wang; Jun Wang; Shengduo Polo Pei; Dongxuan Chen; Guoxin Huang; Meiling Zhang; Gaojing Qu; Wufeng Fan; Hongming Lin; Desheng Li; Bin Pei
Title: Analysis of factors associated early diagnosis in coronavirus disease 2019 (COVID-19) Document date: 2020_4_14
ID: los6q1k4_33
Snippet: In the 108 confirmed COVID-19 cases of this study, 73 of them had their first nucleic acid Cumulative three times of nucleic acid RT-PCR test can reach a relatively ideal diagnosis efficiency (AUC = 0.958), the diagnostic sensitivity is 0.92 (99/108). Therefore, this study also confirms the relatively high false negative rate, which can be miss diagnosis rate, of first nucleic acid test. Based on that, it takes several repeated tests to reach a r.....
Document: In the 108 confirmed COVID-19 cases of this study, 73 of them had their first nucleic acid Cumulative three times of nucleic acid RT-PCR test can reach a relatively ideal diagnosis efficiency (AUC = 0.958), the diagnostic sensitivity is 0.92 (99/108). Therefore, this study also confirms the relatively high false negative rate, which can be miss diagnosis rate, of first nucleic acid test. Based on that, it takes several repeated tests to reach a relatively high diagnosis accuracy. In clinical practice, if suspected cases do not have tested positive, at least three times of nucleic acid RT-PCR test should be conducted for them, in order to decrease miss diagnosis rate. All rights reserved. No reuse allowed without permission. the author/funder, who has granted medRxiv a license to display the preprint in perpetuity.
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