Author: Yong Gao; Yi Yuan; Tuan Tuan Li; Wu Xiao Wang; Yong Xiu Li; Ang Li; Feng Ming Han
Title: Evaluation the auxiliary diagnosis value of antibodies assays for detection of novel coronavirus (SARS-Cov-2) causing an outbreak of pneumonia (COVID-19) Document date: 2020_3_30
ID: 8mx5kowl_28
Snippet: It should be noted that there were still false positive and false negative results for antibodies assay. When IgM and IgG levels are below the detection limit, the test results would be negative. Furthermore, IgM antibodies would gradually decrease and disappear after 2 weeks, so that the IgM level might be below its peak and not detectable in some cases.Meanwhile, the difference in individual immune response might result in the false negative re.....
Document: It should be noted that there were still false positive and false negative results for antibodies assay. When IgM and IgG levels are below the detection limit, the test results would be negative. Furthermore, IgM antibodies would gradually decrease and disappear after 2 weeks, so that the IgM level might be below its peak and not detectable in some cases.Meanwhile, the difference in individual immune response might result in the false negative results in suspected cases (19) (20) . Patients who do not produce antibodies, or who produce antibodies relatively late, might have a relapse once their immunity is reduced.
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