Author: Maja von Cube; Marlon Grodd; Martin Wolkewitz; Derek Hazard; Jerome Lambert
Title: Harmonizing heterogeneous endpoints in COVID-19 trials without loss of information - an essential step to facilitate decision making Document date: 2020_4_3
ID: bsddxgx2_16
Snippet: To obtain a detailed understanding of potential treatment effects, we propose the multistate model shown in Figure 1 For clinical trials that have already been started, we highly recommend to provide the stacked probability plots. Specifically clinical trials using the categorical endpoints recommended by the WHO R&D Blueprint expert group have all the necessary information available for this detailed analysis......
Document: To obtain a detailed understanding of potential treatment effects, we propose the multistate model shown in Figure 1 For clinical trials that have already been started, we highly recommend to provide the stacked probability plots. Specifically clinical trials using the categorical endpoints recommended by the WHO R&D Blueprint expert group have all the necessary information available for this detailed analysis.
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