Author: Robin Franklin; Adam Young; Bjoern Neumann; Rocio Fernandez; Alexis Joannides; Amir Reyahi; Yorgo Modis
Title: Homologous protein domains in SARS-CoV-2 and measles, mumps and rubella viruses: preliminary evidence that MMR vaccine might provide protection against COVID-19 Document date: 2020_4_10
ID: nd5r4yt4_6
Snippet: Sequence homology searches (DELTA-BLAST search followed by iterated PSI-BLAST searches) of paramyxovirus sequences using SARS-CoV-2 as the query. A homology model of the postfusion structure of SARS-CoV-2 S2 based on the postfusion structure of SARS-CoV-1 S2 [Walls et al, 2017] was constructed to asses overall similarities in fold homology with a model of measles virus F based on the postfusion structure of human parainfluenza virus 3 (HPIV3) F [.....
Document: Sequence homology searches (DELTA-BLAST search followed by iterated PSI-BLAST searches) of paramyxovirus sequences using SARS-CoV-2 as the query. A homology model of the postfusion structure of SARS-CoV-2 S2 based on the postfusion structure of SARS-CoV-1 S2 [Walls et al, 2017] was constructed to asses overall similarities in fold homology with a model of measles virus F based on the postfusion structure of human parainfluenza virus 3 (HPIV3) F [Yin et al, 2005] .
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