Author: Ben Longdon; Jonathan P Day; Joel M Alves; Sophia CL Smith; Thomas M Houslay; John E McGonigle; Lucia Tagliaferri; Francis M Jiggins
Title: Host shifts result in parallel genetic changes when viruses evolve in closely related species Document date: 2017_11_28
ID: ithoxu6k_27
Snippet: In conclusion, we have found that host relatedness can be important in determining how viruses 175 evolve when they find themselves in a new host. This study suggests that while some genetic 176 changes will be found only in specific hosts, we frequently see the same changes occurring in closely 177 related host species. These phylogenetic patterns suggest that mutations that adapt a virus to one 178 host may also adapt it to closely related host.....
Document: In conclusion, we have found that host relatedness can be important in determining how viruses 175 evolve when they find themselves in a new host. This study suggests that while some genetic 176 changes will be found only in specific hosts, we frequently see the same changes occurring in closely 177 related host species. These phylogenetic patterns suggest that mutations that adapt a virus to one 178 host may also adapt it to closely related host species. Therefore, there may be a knock-on effect, 179 where a host shift leaves closely related species vulnerable to the new disease.
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