Author: Daniel J Butler; Christopher Mozsary; Cem Meydan; David C Danko; Jonathan Foox; Joel Rosiene; Alon Shaiber; Ebrahim Afshinnekoo; Matthew MacKay; Fritz J Sedlazeck; Nikolay A Ivanov; Maria A Sierra; Diana Pohle; Michael Zeitz; Vijendra Ramlall; Undina Gisladottir; Craig D Westover; Krista Ryon; Benjamin Young; Chandrima Bhattacharya; Phyllis Ruggiero; Bradley W Langhorst; Nathan A Tanner; Justyn Gawrys; Dmitry Meleshko; Dong Xu; Jenny Xiang; Angelika Iftner; Daniela Bezdan; John Sipley; Lin Cong; Arryn Craney; Priya Velu; Ari Melnick; Iman A Hajirasouliha; Thomas Iftner; Mirella Salvatore; Massimo Loda; Lars F Westblade; Shawn Levy; Melissa Cushing; Nicholas P Tatonetti; Marcin Imielinski; Hanna Rennert; Christopher Mason
Title: Host, Viral, and Environmental Transcriptome Profiles of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Document date: 2020_4_20
ID: kyoa5gsf_71
Snippet: We compared usage of ACE inhibitors in an observational cohort analysis of 8,278 patients with suspected SARS-CoV-2 infection (4,574 of which tested positive). ACE inhibitors are commonly taken continuously for several years (Bonarjee et al., 2001) . We defined a cohort of ACE inhibitor-exposed patients as those that have an ACE inhibitor prescription order sometime after January 1st, 2019. We compared the frequency of ACE inhibitor exposure in t.....
Document: We compared usage of ACE inhibitors in an observational cohort analysis of 8,278 patients with suspected SARS-CoV-2 infection (4,574 of which tested positive). ACE inhibitors are commonly taken continuously for several years (Bonarjee et al., 2001) . We defined a cohort of ACE inhibitor-exposed patients as those that have an ACE inhibitor prescription order sometime after January 1st, 2019. We compared the frequency of ACE inhibitor exposure in three cohort comparisons: i. SARS-CoV-2 tested positive patients versus SARS-CoV-2 tested negative patients, ii. SARS-CoV-2 positive patients who require mechanical ventilation versus those who did not, and iii. SARS-CoV-2 positive patient survival versus death.
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