Author: Timothy A. Dinh; Ramja Sritharan; F. Donelson Smith; Adam B. Francisco; Rosanna K. Ma; Rodica P. Bunaciu; Matt Kanke; Charles G. Danko; Andrew P. Massa; John D. Scott; Praveen Sethupathy
Title: Hotspots of aberrant enhancer activity in fibrolamellar carcinoma reveal molecular mechanisms of oncogenesis and intrinsic drug resistance Document date: 2020_1_18
ID: bf4qpsy7_45
Snippet: Samples from C57BL/6N mice were obtained for a previous study (Dinh et al., 2019) and remaining samples were used for this study. Briefly, female 6-10 week old C57BL/6N mice were subjected to hydrodynamic tail-vein injection with sterile 0.9% NaCl and 20 µg transposon and CMB-SB13 transposase (1:5 molar ratio). The transposon plasmid expressed human DNAJB1-PRKACA or an empty control. 3,5-diethoxycarbonyl-1,4-dihydrocollidine (DDC, 0.1%) diet was.....
Document: Samples from C57BL/6N mice were obtained for a previous study (Dinh et al., 2019) and remaining samples were used for this study. Briefly, female 6-10 week old C57BL/6N mice were subjected to hydrodynamic tail-vein injection with sterile 0.9% NaCl and 20 µg transposon and CMB-SB13 transposase (1:5 molar ratio). The transposon plasmid expressed human DNAJB1-PRKACA or an empty control. 3,5-diethoxycarbonyl-1,4-dihydrocollidine (DDC, 0.1%) diet was administered after tail-vein injection.
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