Author: Longlong Si; Haiqing Bai; Melissa Rodas; Wuji Cao; Crystal Yur Oh; Amanda Jiang; Atiq Nurani; Danni Y Zhu; Girija Goyal; Sarah Gilpin; Rachelle Prantil-Baun; Donald E. Ingber
Title: Human organs-on-chips as tools for repurposing approved drugs as potential influenza and COVID19 therapeutics in viral pandemics Document date: 2020_4_14
ID: mrgw2mnx_5
Snippet: These studies were initiated prior to the COVID19 pandemic, and so we began by exploring whether Organ Chip technology 4 can be used to create a preclinical model of influenza virus infection and pathogenesis that effectively mimics human lung airway epithelial, endothelial, and immune cell responses in vitro. The human Airway Chip is a microfluidic device that contains two parallel microchannels separated by an extracellular matrix-coated porous.....
Document: These studies were initiated prior to the COVID19 pandemic, and so we began by exploring whether Organ Chip technology 4 can be used to create a preclinical model of influenza virus infection and pathogenesis that effectively mimics human lung airway epithelial, endothelial, and immune cell responses in vitro. The human Airway Chip is a microfluidic device that contains two parallel microchannels separated by an extracellular matrix-coated porous membrane 6,7 . Primary human lung airway basal stem author/funder. All rights reserved. No reuse allowed without permission.
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