Selected article for: "antiviral drug discovery design and Zika protease"
Author: Liangzhong Lim; Amrita Roy; Jianxing Song
Title: Identification of a Zika NS2B-NS3pro pocket susceptible to allosteric inhibition by small molecules including qucertin rich in edible plants
  • Document date: 2016_10_1
    • ID: gfiukh90_5
    Snippet: The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/078543 doi: bioRxiv preprint emphasizes the irreplaceable role of the Zika protease as a target for antiviral drug discovery/design. As facilitated by our previous studies on Dengue NS2B-NS3pro (12), we started to work on Zika NS2B-NS3pro immediately after the outbreak of Zika and successfully obtained several active forms of recombinant Zika NS2.....
    Document: The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/078543 doi: bioRxiv preprint emphasizes the irreplaceable role of the Zika protease as a target for antiviral drug discovery/design. As facilitated by our previous studies on Dengue NS2B-NS3pro (12), we started to work on Zika NS2B-NS3pro immediately after the outbreak of Zika and successfully obtained several active forms of recombinant Zika NS2B-NS3pro. Furthermore, we attempted to discover its inhibitors from both synthetic compound library and edible plants/traditional herbal medicines to fight Zika.

    Search related documents:
    Co phrase search for related documents
    • active form and drug discovery: 1, 2, 3, 4, 5
    • active form and herbal medicine: 1
    • active form and previous study: 1
    • antiviral drug discovery and compound library: 1, 2, 3
    • antiviral drug discovery and drug discovery: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73
    • antiviral drug discovery and irreplaceable role: 1
    • antiviral drug discovery and Zika outbreak: 1
    • antiviral drug discovery and Zika protease: 1
    • antiviral drug discovery and Zika protease irreplaceable role: 1
    • antiviral drug discovery design and drug discovery: 1, 2, 3, 4, 5, 6
    • antiviral drug discovery design and irreplaceable role: 1
    • antiviral drug discovery design and Zika outbreak: 1
    • antiviral drug discovery design and Zika protease: 1
    • antiviral drug discovery design and Zika protease irreplaceable role: 1
    • antiviral drug discovery design target and drug discovery: 1
    • antiviral drug discovery design target and irreplaceable role: 1
    • antiviral drug discovery design target and Zika outbreak: 1
    • antiviral drug discovery design target and Zika protease: 1
    • antiviral drug discovery design target and Zika protease irreplaceable role: 1