Author: Hema Kothari; Corey M. Williams; Chantel McSkimming; Mythili Vigneshwar; Eli R. Zunder; Coleen A. McNamara
Title: Identification of Human Immune Cell Subtypes Most Vulnerable to IL-1ß-induced Inflammatory Signaling Using Mass Cytometry Document date: 2020_4_19
ID: 5rhn7gom_30
Snippet: While studies over the past decades have provided significant insights into pathophysiological mechanisms that lead to dysregulated production of IL-1β, knowledge about the specific human immune cell types that IL-1β targets is still limited. We have identified the key human immune cell subtypes that are most vulnerable to IL-1β, as well as the subset-specific signaling pathways that are activated......
Document: While studies over the past decades have provided significant insights into pathophysiological mechanisms that lead to dysregulated production of IL-1β, knowledge about the specific human immune cell types that IL-1β targets is still limited. We have identified the key human immune cell subtypes that are most vulnerable to IL-1β, as well as the subset-specific signaling pathways that are activated.
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