Author: Martin Bartas; Václav Brázda; Natália Bohálová; Alessio Cantara; Adriana Volná; Tereza Stachurová; Katerina Malachová; Eva B. Jagelská; Otília Porubiaková; Jirí Cerven; Petr Pecinka
Title: In-depth Bioinformatic Analyses of Human SARS-CoV-2, SARS-CoV, MERS-CoV, and Other Nidovirales Suggest Important Roles of Noncanonical Nucleic Acid Structures in Their Lifecycles Document date: 2020_4_11
ID: d3q0xel1_39
Snippet: . CC-BY-ND 4.0 International license author/funder. It is made available under a The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.04.09.031252 doi: bioRxiv preprint FIGURE 6 | RNA fold (Lorenz et al., 2011) prediction for SARS-CoV-2 RNA molecule (left) and random sequence negative control (right). This figure shows a high level of SARS-CoV-2 genome folding via complementarity of particular.....
Document: . CC-BY-ND 4.0 International license author/funder. It is made available under a The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.04.09.031252 doi: bioRxiv preprint FIGURE 6 | RNA fold (Lorenz et al., 2011) prediction for SARS-CoV-2 RNA molecule (left) and random sequence negative control (right). This figure shows a high level of SARS-CoV-2 genome folding via complementarity of particular RNA regions and forming of hairpins and/or cruciforms. RNA fold prediction was carried out using default parameters via Galaxy webserver (Afgan et al., 2018) , which enables queries of lengths longer than 10,000 nucleotides.
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